Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646915 | 0.82 | CYP1A2 (0.52) | KMT2AALDH1A1CYP1A2CES2CES1 | |
| SCHEMBL21199897 | 0.81 | AOC3 (0.53) | L3MBTL1KMT2AMEN1RAB9ANPSR1 | |
| SCHEMBL628797 | 0.81 | LMNA (0.56) | L3MBTL1KMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL27553229 | 0.79 | AOC3 (0.56) | L3MBTL1KMT2AALDH1A1MAPTFFAR1 | |
| SCHEMBL27553231 | 0.79 | AOC3 (0.56) | L3MBTL1KMT2AALDH1A1MAPTFFAR1 | |
| SCHEMBL4758820 | 0.79 | BRD4 (0.48) | KMT2AMEN1LMNAFFAR1CYP1A2 | |
| SCHEMBL3647766 | 0.79 | GSK3B (0.42) | ALDH1A1GSK3BCYP1A2 | |
| SCHEMBL3649808 | 0.79 | HDAC3 (0.44) | KMT2AALDH1A1MEN1NPSR1LMNA | |
| SCHEMBL2655629 | 0.79 | CES2 (0.48) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL22319291 | 0.79 | CES2 (0.48) | KMT2AALDH1A1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633886-A1 | PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES | PHARMACIA & UPJOHN COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |