SCHEMBL9216137

SCHEMBL9216137

CC(C)COc1c(N(C=O)c2ccc(F)cc2F)c(C(F)(F)Cl)nn1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9544901 0.92 LMNA (0.34) LMNANPSR1
SCHEMBL9217007 0.82 LMNA (0.36) LMNANPSR1
SCHEMBL9216348 0.81 LMNA (0.36) LMNANPSR1
SCHEMBL9545491 0.80 LMNA (0.35) LMNANPSR1
SCHEMBL9544298 0.76 NPSR1 (0.44) LMNANPSR1
SCHEMBL9214398 0.75 NPSR1 (0.41) LMNANPSR1
SCHEMBL9217214 0.74 NPSR1 (0.45) LMNANPSR1
SCHEMBL9209425 0.73 LMNA (0.48) LMNANPSR1
SCHEMBL9544365 0.73 NPSR1 (0.36) LMNANPSR1
SCHEMBL9216835 0.72 NPSR1 (0.57) LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644879-A1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES RHONE POULENC AGRICULTURE LTD. (GB) 1995-03-29 EP claimed
WO-1993025535-A1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES RHONE POULENC AGRICULTURE LTD. (GB) 1993-12-23 WO claimed
EP-0644879-A1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES RHONE POULENC AGRICULTURE LTD. (GB) 1995-03-29 EP disclosed
WO-1993025535-A1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES RHONE POULENC AGRICULTURE LTD. (GB) 1993-12-23 WO disclosed