Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGFR | P43088 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 3/20 | 0.35 |
| ▸ | F3 | P13726 | 3/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224430 | 0.92 | GHSR (0.45) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL9223283 | 0.92 | GHSR (0.46) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL9275499 | 0.91 | GHSR (0.47) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9223271 | 0.91 | GHSR (0.50) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL9223287 | 0.90 | GHSR (0.44) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL9216422 | 0.90 | GHSR (0.44) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL9107726 | 0.90 | AGTR1 (0.45) | GHSRAGTR1PTGER1PTGER3PTGER4 | |
| SCHEMBL9223402 | 0.90 | XIAP (0.38) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL9107089 | 0.87 | GHSR (0.57) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL7791678 | 0.85 | GHSR (0.57) | GHSRAGTR1XIAPF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003289-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |