Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | FABP2 | P12104 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382273 | 0.88 | NPC1 (0.52) | NPC1SMN1; SMN2ALDH1A1PPARAFABP2 | |
| SCHEMBL11233255 | 0.85 | EPHX2 (0.48) | NPC1SMN1; SMN2ALDH1A1PPARAPPARG | |
| SCHEMBL3690908 | 0.79 | EPHX2 (0.71) | NPC1SMN1; SMN2ALDH1A1PPARAFABP2 | |
| SCHEMBL11233259 | 0.78 | SMN1; SMN2 (0.51) | NPC1SMN1; SMN2RAB9AGAAEPHX1 | |
| SCHEMBL11246295 | 0.77 | CHRM1 (0.49) | NPC1SMN1; SMN2ALDH1A1RAB9AMAPT | |
| SCHEMBL17789183 | 0.74 | PPARA (0.60) | NPC1SMN1; SMN2ALDH1A1PPARAFABP2 | |
| SCHEMBL11236871 | 0.73 | EPHX2 (0.52) | NPC1SMN1; SMN2ALDH1A1PPARAPPARG | |
| SCHEMBL11241423 | 0.73 | EPHX1 (0.44) | NPC1SMN1; SMN2ALDH1A1PPARGCYP2D6 | |
| SCHEMBL16562294 | 0.73 | KMT2A (0.70) | NPC1SMN1; SMN2ALDH1A1PPARAFABP2 | |
| SCHEMBL3573449 | 0.73 | NPC1 (0.64) | NPC1SMN1; SMN2ALDH1A1PPARAFABP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7138218-A | — | — | None | — | — | JP | disclosed |
| JP-H07138218-A | OPTICALLY ACTIVE OXYACETIC ACID DERIVATIVE | KURARAY CO LTD | 1995-05-30 | — | — | JP | disclosed |