Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241426 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1HPGDNPC1RAB9A | |
| SCHEMBL11236872 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1HPGDNPC1RAB9A | |
| SCHEMBL9216152 | 0.78 | NPC1 (0.55) | SMN1; SMN2NPSR1HPGDNPC1RAB9A | |
| SCHEMBL11246292 | 0.77 | LMNA (0.48) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL11237830 | 0.76 | HPGD (0.44) | SMN1; SMN2HPGDGAAPTGER4TAS1R3 | |
| SCHEMBL10338889 | 0.74 | UTS2R (0.64) | SMN1; SMN2NPC1RAB9APTGER4TAS1R3 | |
| SCHEMBL23130344 | 0.74 | IDO1 (0.58) | SMN1; SMN2TAS1R3TAS1R1IDO1EPHX1 | |
| SCHEMBL1922928 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1GAALMNAGPR139 | |
| SCHEMBL7676189 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1GAALMNAGPR139 | |
| SCHEMBL31498841 | 0.72 | GPR139 (0.72) | SMN1; SMN2HPGDNPC1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318923-A | HYPOLIPEMIC AGENT | KAKEN CHEMICAL CO., LTD. (JP) | 1982-03-09 | — | — | US | disclosed |