Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236871 | 0.88 | EPHX2 (0.52) | EPHX2EPHX1ALDH1A1CASP1HSD17B10 | |
| SCHEMBL11241423 | 0.88 | EPHX1 (0.44) | EPHX2EPHX1ALDH1A1CASP1HSD17B10 | |
| SCHEMBL9216152 | 0.85 | NPC1 (0.55) | EPHX2EPHX1ALDH1A1CASP1HSD17B10 | |
| SCHEMBL11233123 | 0.79 | EPHX2 (0.42) | EPHX2EPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL11382273 | 0.74 | NPC1 (0.52) | EPHX2EPHX1ALDH1A1PPARGPPARA | |
| SCHEMBL11233259 | 0.71 | SMN1; SMN2 (0.51) | EPHX1NPC1RAB9ALMNAHPGD | |
| SCHEMBL10110920 | 0.70 | METAP2 (0.47) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL8403428 | 0.70 | METAP2 (0.47) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11356710 | 0.69 | HAO1 (0.46) | ALDH1A1CASP1NPC1RAB9AMEN1 | |
| SCHEMBL21057117 | 0.69 | LDHA (0.54) | EPHX1ALDH1A1PPARGPPARANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318923-A | HYPOLIPEMIC AGENT | KAKEN CHEMICAL CO., LTD. (JP) | 1982-03-09 | — | — | US | disclosed |