Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211282 | 0.83 | MAP3K14 (0.41) | MAP3K14METKDRKDM2BKDM4C | |
| SCHEMBL9224323 | 0.80 | MAPK14 (0.40) | IDO1MAPTLMNAAHRALDH1A1 | |
| SCHEMBL9019167 | 0.80 | MAPK14 (0.40) | METKDRIDO1MAPTLMNA | |
| SCHEMBL7507481 | 0.79 | ABL1 (0.37) | MAP3K14METKDRMAPTLMNA | |
| SCHEMBL9222935 | 0.77 | AHR (0.39) | METKDRIDO1MAPTLMNA | |
| SCHEMBL9019068 | 0.76 | MAPT (0.38) | IDO1MAPTLMNAAHRALDH1A1 | |
| SCHEMBL9336008 | 0.76 | AHR (0.36) | IDO1MAPTLMNAAHRHPGD | |
| SCHEMBL9055776 | 0.75 | P2RX3 (0.37) | METKDRIDO1KDM2BKDM4C | |
| SCHEMBL10590186 | 0.74 | TDP1 (0.46) | MAPTPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL7500290 | 0.74 | AHR (0.37) | METKDRIDO1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484614-B1 | N-acylated arylpyrroles useful as insecticidal, acaricidal, nematicidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1995-05-24 | — | — | EP | claimed |
| EP-0484614-A2 | N-acylated arylpyrroles useful as insecticidal, acaricidal, nematicidal and molluscicidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-05-13 | — | — | EP | claimed |
| EP-0484614-B1 | N-acylated arylpyrroles useful as insecticidal, acaricidal, nematicidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0484614-A2 | N-acylated arylpyrroles useful as insecticidal, acaricidal, nematicidal and molluscicidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-05-13 | — | — | EP | disclosed |