SCHEMBL9216477

SCHEMBL9216477

O=S(=O)(O)C(Nc1ccccc1)S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
TDP1 Q9NUW8 2/20 0.44
ACP1 P24666 2/20 0.44
SRC P12931 1/20 0.42
KEAP1 Q14145 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 3/20 0.41
IL1RN P18510 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40
TP53 P04637 1/20 0.39
EPHX1 P07099 1/20 0.39
EPHX2 P34913 1/20 0.39
CDK9 P50750 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
PGR P06401 1/20 0.39
LMNA P02545 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1608004 0.78 TDP1 (0.52) CA12CA9TDP1ACP1SRC
SCHEMBL10033917 0.77 SRC (0.47) CA12CA9TDP1ACP1SRC
SCHEMBL7718606 0.76 CA12 (0.48) CA12CA9TDP1KEAP1CA1
SCHEMBL21518442 0.75 TDP1 (0.48) CA12CA9TDP1ACP1SRC
SCHEMBL10481891 0.75 CA12 (0.41) CA12CA9TDP1ACP1SRC
SCHEMBL1608192 0.75 TDP1 (0.48) CA12CA9TDP1ACP1SRC
Sulfuric Acid SCHEMBL10588282 0.74 ALDH1A1 (0.55) CA12CA9TDP1ACP1KEAP1
SCHEMBL1009042 0.74 TDP1 (0.42) CA12CA9TDP1ACP1SRC
SCHEMBL6531556 0.74 CA12 (0.40) CA12CA9TDP1ACP1SRC
SCHEMBL9574264 0.72 TDP1 (0.45) CA12CA9TDP1KEAP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995002848-A1 MULTIFUNCTIONAL AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-26 WO disclosed