Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 2/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9216507 | 0.91 | HRH3 (0.43) | HRH3MEN1KMT2ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9221539 | 0.87 | HRH3 (0.46) | HRH3MEN1KMT2ASMN1; SMN2LCAT | |
| SCHEMBL9211798 | 0.86 | HRH3 (0.48) | HRH3MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1562360 | 0.84 | MAPT (0.43) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL9219556 | 0.82 | HRH3 (0.50) | HRH3MEN1KMT2ASMN1; SMN2LCAT | |
| SCHEMBL9200711 | 0.81 | LMNA (0.56) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL9445115 | 0.76 | CYP1A2 (0.58) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL2004943 | 0.76 | HRH3 (0.49) | HRH3MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9200293 | 0.75 | NR1I2 (0.40) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL9214199 | 0.75 | OGA (0.39) | MEN1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320032-B1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-01-18 | — | — | EP | disclosed |
| US-5231184-A | Viricide intermediate | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-27 | — | — | US | disclosed |
| US-5106973-A | Viricide intermediates | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-21 | — | — | US | disclosed |
| US-4992433-A | Viricides | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-12 | — | — | US | disclosed |
| EP-0320032-A1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-14 | — | — | EP | disclosed |