Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 4/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13444835 | 0.85 | DUT (0.74) | DUTALDH1A1LMNAALBPOLB | |
| SCHEMBL9223713 | 0.81 | DUT (0.69) | DUTALDH1A1LMNAALBPOLB | |
| SCHEMBL30976639 | 0.81 | DUT (0.67) | DUTALDH1A1LMNAALBPOLB | |
| SCHEMBL13444856 | 0.81 | DUT (0.67) | DUTALDH1A1LMNAALBPOLB | |
| SCHEMBL19927650 | 0.79 | DUT (0.65) | DUTP2RY14SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL5963993 | 0.79 | DUT (0.65) | DUTTOP2AP2RY14SLC28A1SLC28A2 | |
| SCHEMBL26133880 | 0.79 | DUT (0.65) | DUTP2RY14SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1879258 | 0.79 | DUT (0.65) | DUTALDH1A1LMNAALBPOLB | |
| SCHEMBL1879256 | 0.79 | DUT (0.65) | DUTALDH1A1LMNAALBPOLB | |
| SCHEMBL8540687 | 0.78 | DUT (0.64) | DUTALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455339-A | Method for the preparation of 2',3'-dideoxy and 2',3'-dideoxydide-hydro nucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-10-03 | — | — | US | disclosed |