Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 16/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 11/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530214 | 0.87 | ADRA2C (0.49) | ADRA2CADRA1AADRA1B | |
| SCHEMBL9209192 | 0.87 | ALDH1A1 (0.53) | FABP4FABP5ADRA2CADRA1AADRA1B | |
| SCHEMBL9208872 | 0.84 | POLB (0.55) | FABP4FABP5ADRA2CADRA1AADRA1B | |
| SCHEMBL20090414 | 0.83 | EPHX2 (0.49) | FABP4FABP5ADRA2CADRA1AADRA1B | |
| SCHEMBL17170051 | 0.83 | ADRA2C (0.52) | FABP4ADRA2CADRA1AADRA1B | |
| SCHEMBL1120903 | 0.81 | ADRA2C (0.51) | FABP4FABP5ADRA2CADRA1AADRA1B | |
| SCHEMBL14594642 | 0.81 | ALDH1A1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL9209804 | 0.80 | ADRA2C (0.57) | FABP4FABP5ADRA2CADRA1AADRA1B | |
| SCHEMBL414609 | 0.80 | BRAF (0.56) | FABP4FABP5 | |
| SCHEMBL3524481 | 0.80 | POLB (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1744899-A | Piperidine derivatives as CCR5 antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1043526-C | Sulfoneanilide derivative and application of same in medicine | NIPPON SHINYAKU CO LTD (JP) | 1999-06-02 | — | — | CN | disclosed |
| EP-0538469-B1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5360822-A | FOR TREATING URINARY INCONTINENCE IN ANIMALS AND HUMANS | NIPPON SHINYAKU CO. LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0538469-A1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-28 | — | — | EP | disclosed |