Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11694274 | 0.95 | FFAR4 (0.68) | FFAR4FFAR1GPR84PPARGPPARD | |
| Sulfuric Acid SCHEMBL11698934 | 0.93 | FFAR4 (0.66) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL1275084 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL17911294 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL10952918 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL4402579 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL1274520 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL8633366 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL3758559 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL8539791 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682670-A1 | DEOXYGENATION OF CIS VICINAL DIOLS | RAYLO CHEMICALS INC. (CA) | 1995-11-22 | — | — | EP | disclosed |
| WO-1994018214-A1 | DEOXYGENATION OF CIS VICINAL DIOLS | TEROCHEM LABORATORIES LIMITED (CA) | 1994-08-18 | — | — | WO | disclosed |