Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IL6ST | P40189 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217065 | 1.00 | TDP1 (0.49) | TDP1IL6STMAPK1SMN1; SMN2TACR1 | |
| SCHEMBL9217060 | 1.00 | TDP1 (0.49) | TDP1IL6STMAPK1SMN1; SMN2TACR1 | |
| SCHEMBL9216981 | 0.93 | IL6ST (0.55) | TDP1IL6STALDH1A1FAAH | |
| SCHEMBL7268237 | 0.93 | IL6ST (0.55) | TDP1IL6STALDH1A1FAAH | |
| SCHEMBL9216987 | 0.93 | IL6ST (0.55) | TDP1IL6STALDH1A1FAAH | |
| SCHEMBL7268241 | 0.93 | IL6ST (0.55) | TDP1IL6STALDH1A1FAAH | |
| SCHEMBL7272206 | 0.82 | IL6ST (0.48) | IL6STMAPK1TACR1 | |
| SCHEMBL9739731 | 0.80 | IL6ST (0.59) | IL6ST | |
| SCHEMBL9739729 | 0.80 | IL6ST (0.59) | IL6ST | |
| SCHEMBL9220378 | 0.79 | KMT2A (0.45) | IL6STSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |