Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.59 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPA3 | P15088 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739729 | 1.00 | IL6ST (0.59) | IL6STCPA1CPB1CPA3CPB2 | |
| SCHEMBL7277218 | 0.87 | IL6ST (0.53) | IL6STSTAT3NAAAIDH1CYP1A2 | |
| SCHEMBL7277227 | 0.87 | IL6ST (0.53) | IL6STSTAT3NAAAIDH1CYP1A2 | |
| SCHEMBL7277223 | 0.87 | IL6ST (0.53) | IL6STSTAT3NAAAIDH1CYP1A2 | |
| SCHEMBL9216981 | 0.86 | IL6ST (0.55) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL9216987 | 0.86 | IL6ST (0.55) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL7268241 | 0.86 | IL6ST (0.55) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL7277673 | 0.86 | IL6ST (0.52) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL7268237 | 0.86 | IL6ST (0.55) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL17418481 | 0.85 | IL6ST (0.64) | IL6STSTAT3NAAAIDH1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |