Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268241 | 1.00 | IL6ST (0.55) | IL6STHPGDSTAT3NPC1RAB9A | |
| SCHEMBL9216981 | 1.00 | IL6ST (0.55) | IL6STHPGDSTAT3NPC1RAB9A | |
| SCHEMBL7268237 | 1.00 | IL6ST (0.55) | IL6STHPGDSTAT3NPC1RAB9A | |
| SCHEMBL9217065 | 0.93 | TDP1 (0.49) | IL6STFAAHALDH1A1TDP1 | |
| SCHEMBL9217060 | 0.93 | TDP1 (0.49) | IL6STFAAHALDH1A1TDP1 | |
| SCHEMBL9217062 | 0.93 | TDP1 (0.49) | IL6STFAAHALDH1A1TDP1 | |
| SCHEMBL7272206 | 0.88 | IL6ST (0.48) | IL6STSTAT3NPC1RAB9AKMT2A | |
| SCHEMBL9739731 | 0.86 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL9739729 | 0.86 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL9225396 | 0.85 | IL6ST (0.49) | IL6STSTAT3KMT2AFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |