Phosphoric Acid

Phosphoric Acid

SCHEMBL921725

C=CC(=O)NC(C)CC.O=P(O)(O)O

nearest known ligand 0.55

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.55
MMP2 P08253 2/20 0.55
MMP3 P08254 1/20 0.55
TSHR P16473 2/20 0.52
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ACACB O00763 2/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
MMP8 P22894 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 1/20 0.37
MAPK1 P28482 2/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319728 0.92
SCHEMBL1315706 0.92
SCHEMBL8401460 0.92
SCHEMBL7447123 0.90 TSHR (0.58) MMP1MMP2MMP3TSHRPKM
Hydrogen Sulfide SCHEMBL28195736 0.90 TSHR (0.58) MMP1MMP2MMP3TSHRPKM
Ammonia Solution, Strong SCHEMBL28050078 0.90 TSHR (0.58) MMP1MMP2MMP3TSHRPKM
SCHEMBL14344159 0.90 TSHR (0.58) MMP1MMP2MMP3TSHRPKM
Dimethylamine SCHEMBL28317954 0.88 TSHR (0.56) MMP1MMP2MMP3TSHRPKM
Acetone SCHEMBL28215913 0.88 TSHR (0.56) MMP1MMP2MMP3TSHRPKM
Phosphonic Acid SCHEMBL18424925 0.85 TSHR (0.52) MMP1MMP2MMP3TSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745464-A Phosphate-containing high-adaptability early-strength polycarboxylate superplasticizer and preparation method and application thereof 广州市建筑科学研究院有限公司 2021-05-04 CN claimed
CN-106459367-B Polyurethanes with reduced aldehyde emissions 巴斯夫欧洲公司 2019-12-06 CN disclosed
US-10329372-B2 Polyurethanes with reduced aldehyde emission BASF SE (DE) 2019-06-25 US disclosed
US-20180186923-A1 POLYURETHANES WITH REDUCED ALDEHYDE EMISSION BASF SE (DE) 2018-07-05 US disclosed
CN-106459367-A Polyurethanes with reduced aldehyde emission 巴斯夫欧洲公司 2017-02-22 CN disclosed
US-8426635-B2 Process for preparing solid alkaline earth metal salts of secondary paraffinsulphonic acids CLARIANT FINANCE (BVI) LIMITED (VG) 2013-04-23 US disclosed
EP-2262882-B1 PROCESS FOR PREPARING SOLID ALKALINE EARTH METAL SALTS OF SECONDARY PARAFFINSULPHONIC ACIDS CLARIANT FINANCE BVI LTD (VG) 2012-12-12 EP disclosed
US-20110021812-A1 Process For Preparing Solid Alkaline Earth Metal Salts Of Secondary Paraffinsulphonic Acids CLARIANT FINANCE (BVI) LIMITED (VG) 2011-01-27 US disclosed
EP-1487955-B1 AMMONIUM NITRILES AND THE USE THEREOF AS HYDROPHOBIC BLEACHING ACTIVATORS CLARIANT PRODUKTE DEUTSCHLAND (DE) 2008-05-21 EP disclosed
EP-1920041-A1 WASHING AND CLEANING AGENTS CONTAINING 1,3,5-TRIACETYL-2,4-DIOXO-1,3,5-HEXAHYDROTRIAZINE AS A BLEACH ACTIVATOR Clariant Produkte (Deutschland) GmbH (DE) 2008-05-14 EP disclosed
EP-1487955-A1 AMMONIUM NITRILES AND THE USE THEREOF AS HYDROPHOBIC BLEACHING ACTIVATORS Clariant GmbH (DE) 2004-12-22 EP disclosed
EP-1148118-B1 Detergent comprising dendrimeric ligands and their metallo-complexes as bleach activators CLARIANT GMBH (DE) 2003-12-03 EP disclosed
WO-2003078561-A1 AMMONIUM NITRILES AND THE USE THEREOF AS HYDROPHOBIC BLEACHING ACTIVATORS CLARIANT GMBH (DE) 2003-09-25 WO disclosed
US-6545147-B1 E.g., a bicyclic manganese complex containing a bridging 2,6-bis(1,4,7-triazacyclononan-1-ylmethyl)4-methylphenoxide ligand, two bridging acetate groups and two perchlorate anions CLARIANT GMBH (DE) 2003-04-08 US disclosed
US-6506218-B2 Peroxide and a dendrimeric polyamine or polyamideamine containing benzylideneimino end groups and their metal complexes CLARIANT GMBH (DE) 2003-01-14 US disclosed
US-20020091071-A1 Process for bleaching paper using bleaching-active dendrimer ligands CLARIANT GMBH 2002-07-11 US disclosed
US-6365562-B1 Laundry detergents and cleaners comprising bleaching-active dendrimer ligands and metal complexes thereof CLARIANT GMBH (DE) 2002-04-02 US disclosed
US-20020028753-A1 Laundry detergents and cleaners comprising bleaching-active dendrimer ligands and metal complexes thereof CLARIANT GMBH 2002-03-07 US disclosed
EP-1148118-A1 Detergent comprising dendrimeric ligands and their metallo-complexes as bleach activators Clariant GmbH (DE) 2001-10-24 EP disclosed
EP-1083173-A2 Metal complexes with bleaching activity Clariant GmbH (DE) 2001-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021812-A1 Process For Preparing Solid Alkaline Earth Metal Salts Of Secondary Paraffinsulphonic Acids PMM2, ATP6V1H, ATP6AP1 MMP1 2608/4885MMP2 2038/4885MMP3 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.