⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818106 | 0.97 | — | — | |
| SCHEMBL2386474 | 0.75 | — | — | |
| SCHEMBL17599054 | 0.75 | — | — | |
| SCHEMBL8728552 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL8909828 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL5258376 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL8954347 | 0.71 | — | — | |
| SCHEMBL4915033 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL12130878 | 0.69 | — | — | |
| SCHEMBL8165931 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253362-A1 | ARYL ISOXAZOLINE COMPOUND AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2022-12-08 | — | — | WO | claimed |
| CN-115433177-A | Aryl isoxazoline compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-113754607-A | Oxadiazole compound and application thereof | 沈阳化工大学 | 2021-12-07 | — | — | CN | claimed |
| US-20210206809-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | VERA THERAPEUTICS INC (US) | 2021-07-08 | — | — | US | claimed |
| EP-2922859-B1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIV CORK (IE) | 2021-05-05 | — | — | EP | claimed |
| US-20200318109-A1 | LNA-G Process | F. HOFFMANN-LA ROCHE AG (CH) | 2020-10-08 | — | — | US | claimed |
| US-20200291056-A1 | ACYL-PROTECTED L-LNA-GUANOSINE L-MONOMERS | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2020-09-17 | — | — | US | claimed |
| EP-3601237-A2 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | Trucode Gene Repair, Inc. (US) | 2020-02-05 | — | — | EP | claimed |
| CN-110740994-A | Peptide Nucleic Acid (PNA) monomers with orthogonally protected ester moieties | 特鲁科德基因修复公司 | 2020-01-31 | — | — | CN | claimed |
| EP-3341479-B1 | LNA-G PROCESS | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2019-12-18 | — | — | EP | claimed |
| WO-2002083702-A1 | PROCESS FOR SELECTIVE N-ACYLATION OF PURINE NUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | claimed |
| US-6384071-B2 | ANTITUMOR AGENTS | AVENTIS PHARMA, S.A. (FR) | 2002-05-07 | — | — | US | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-20010021783-A1 | New taxoids, their preparation and pharmaceutical compositions containing them | Rhône-Poulenc Rorer S.A. | 2001-09-13 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| US-5814658-A | Taxoids, their preparation and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1998-09-29 | — | — | US | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |