Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627018 | 0.78 | POLB (0.37) | ALDH1A1KDM4EPOLBNPSR1KMT2A | |
| SCHEMBL5996863 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBNPSR1APAF1 | |
| SCHEMBL3730682 | 0.76 | POLB (0.33) | ALDH1A1KDM4EPOLB | |
| SCHEMBL13174628 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBAPAF1KMT2A | |
| SCHEMBL941690 | 0.63 | KDM4E (0.41) | ALDH1A1KDM4EPOLBAPAF1L3MBTL1 | |
| SCHEMBL908039 | 0.63 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBAPAF1KMT2A | |
| SCHEMBL14908425 | 0.63 | KDM4E (0.41) | ALDH1A1KDM4EPOLBAPAF1L3MBTL1 | |
| SCHEMBL907712 | 0.63 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2ACSNK2A2CSNK2B | |
| SCHEMBL14417042 | 0.61 | GRIK1 (0.36) | ALDH1A1KDM4EKMT2ATSHRGAA | |
| SCHEMBL11359304 | 0.60 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684945-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |