Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217375 | 0.77 | ALDH1A1 (0.38) | ALDH1A1POLBAPAF1LMNANPSR1 | |
| SCHEMBL17627018 | 0.76 | POLB (0.37) | ALDH1A1POLBNPSR1KDM4EHPGD | |
| SCHEMBL3730682 | 0.73 | POLB (0.33) | ALDH1A1POLBKDM4E | |
| SCHEMBL3508465 | 0.72 | FAAH (0.34) | ALDH1A1MGLLDAGLATRPV1 | |
| SCHEMBL5998376 | 0.66 | ALDH1A1 (0.39) | ALDH1A1POLBMGLLKDM4EHPGD | |
| SCHEMBL3712685 | 0.65 | DAGLA (0.34) | KDM4EDAGLAGRIK1GRIA1GRIA2 | |
| SCHEMBL5998647 | 0.64 | NOTUM (0.41) | KDM4E | |
| SCHEMBL13174628 | 0.60 | ALDH1A1 (0.44) | ALDH1A1POLBAPAF1LMNAKDM4E | |
| SCHEMBL907712 | 0.60 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL14417042 | 0.59 | GRIK1 (0.36) | ALDH1A1KDM4EHPGDGRIK1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270706-A1 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270706-A1 | Cyclic amine derivative having heteroaryl ring | F12, F2, H1-3 | ALDH1A1 1073/4885POLB 3995/4885APAF1 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.