Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.53 |
| ▸ | HEXA | P06865 | 4/20 | 0.46 |
| ▸ | HEXB | P07686 | 4/20 | 0.46 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050186 | 0.96 | SIRT1 (0.49) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL9080071 | 0.87 | FTO (0.54) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL9212321 | 0.80 | SIRT1 (0.54) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL7709787 | 0.79 | KMT2A (0.46) | MEN1USP2POLBMAPTHTT | |
| SCHEMBL9219088 | 0.77 | SIRT1 (0.53) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL9042793 | 0.77 | SIRT1 (0.50) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL9080075 | 0.75 | SIRT1 (0.59) | SIRT1HEXAHEXBOGA | |
| SCHEMBL9079634 | 0.75 | SIRT1 (0.50) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL9079400 | 0.74 | SIRT1 (0.52) | SIRT1HEXAHEXBOGAMEN1 | |
| SCHEMBL9079725 | 0.74 | SIRT1 (0.52) | SIRT1HEXAHEXBOGAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |