Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214613 | 0.93 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2RAB9AUSP2NPC1 | |
| SCHEMBL9214687 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9AUSP2NPC1 | |
| Hydrochloric Acid SCHEMBL9217585 | 0.82 | L3MBTL1 (0.48) | ALDH1A1SMN1; SMN2NPC1L3MBTL1KDM4E | |
| SCHEMBL9218007 | 0.79 | L3MBTL1 (0.68) | ALDH1A1SMN1; SMN2RAB9AUSP2NPC1 | |
| SCHEMBL9431510 | 0.79 | L3MBTL1 (0.41) | ALDH1A1GAAL3MBTL1KDM4EATM | |
| Hydrochloric Acid SCHEMBL9215520 | 0.75 | L3MBTL1 (0.52) | ALDH1A1SMN1; SMN2NPC1L3MBTL1KDM4E | |
| SCHEMBL9218757 | 0.74 | TP53 (0.42) | ALDH1A1SMN1; SMN2USP2GAAL3MBTL1 | |
| SCHEMBL9430442 | 0.73 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL9431286 | 0.72 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL9431302 | 0.72 | L3MBTL1 (0.49) | ALDH1A1SMN1; SMN2NPC1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |