SCHEMBL92177

SCHEMBL92177

C=Cc1ccc(COCF)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.36
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
LMNA P02545 2/20 0.31
TP53 P04637 2/20 0.31
PSMD14 O00487 1/20 0.31
MAPT P10636 1/20 0.31
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5066935 0.87 ALDH1A1 (0.55) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL92129 0.84 ALDH1A1 (0.42) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL18868385 0.83 ALDH1A1 (0.50) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL18832287 0.83 ALDH1A1 (0.50) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL1140820 0.81 ALDH1A1 (0.48) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL17075233 0.81 ALDH1A1 (0.48) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL316600 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL18868404 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL18868382 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL8155318 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170259461-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2017-09-14 US disclosed
US-9662809-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2017-05-30 US disclosed
US-20160236379-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2016-08-18 US disclosed
US-9340001-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2016-05-17 US disclosed
US-9314548-B2 Nanostructured surfaces for biomedical/biomaterial applications and processes thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2016-04-19 US disclosed
US-20150148903-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2015-05-28 US disclosed
US-20150101743-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2015-04-16 US disclosed
US-8945441-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2015-02-03 US disclosed
US-20140131915-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-05-15 US disclosed
US-8662878-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-03-04 US disclosed
US-20130228950-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-09-05 US disclosed
US-20130202729-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-08-08 US disclosed
US-8444899-B2 Methods and materials for fabricating microfluidic devices THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-05-21 US disclosed
US-8439666-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-05-14 US disclosed
US-20120256354-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-10-11 US disclosed
US-20120189728-A1 METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM LIQUIDIA TECHNOLOGIES, INC. (US) 2012-07-26 US disclosed
US-8158728-B2 Methods and materials for fabricating microfluidic devices THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-04-17 US disclosed
US-8128393-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2012-03-06 US disclosed
US-7435495-B2 Liquid materials for use in electrochemical cells THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2008-10-14 US disclosed