Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217865 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KMT2AHTTPKMEGFR | |
| SCHEMBL9216639 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2AHTTPKMEGFR | |
| SCHEMBL9216627 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2AHTTPKMEGFR | |
| SCHEMBL9209926 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AHTTPKMMAPT | |
| SCHEMBL9209928 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AHTTPKMMAPT | |
| SCHEMBL9219597 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AHTTPKMMAPT | |
| SCHEMBL9219607 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AHTTPKMMAPT | |
| SCHEMBL9218079 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2AHTTPKMMAPT | |
| SCHEMBL9218067 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2AHTTPKMMAPT | |
| SCHEMBL9215219 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AHTTPKMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475214-B1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5326785-A | Arteriosclerosis andn diseases of the circulatory system | SUNTORY LIMITED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5232941-A | Therapeutic agents for diseases of the circulatory system | SUNTORY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0475214-A1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |