Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218156 | 1.00 | ABCB1 (0.57) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9217495 | 0.88 | ABCB1 (0.60) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9217488 | 0.88 | ABCB1 (0.60) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9218656 | 0.87 | ABCB1 (0.64) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9218647 | 0.87 | ABCB1 (0.64) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9215587 | 0.83 | ABCB1 (0.63) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9215583 | 0.83 | ABCB1 (0.63) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9704223 | 0.81 | ABCB1 (0.55) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL9703981 | 0.81 | ABCB1 (0.55) | ABCB1GPR35MAPTHPGDALDH1A1 | |
| SCHEMBL8440941 | 0.81 | ABCB1 (0.58) | ABCB1GPR35MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412849-B1 | Azole pesticides | AGREVO UK LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0412849-A2 | Azole pesticides | AgrEvo UK Limited (GB) | 1991-02-13 | — | — | EP | disclosed |