Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208064 | 0.90 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9219252 | 0.87 | ALOX5 (0.75) | ALOX5 | |
| SCHEMBL9214653 | 0.84 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL9371449 | 0.79 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL9371614 | 0.78 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9209076 | 0.77 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9219627 | 0.77 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL9229048 | 0.77 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9218747 | 0.76 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9227946 | 0.76 | ALOX5 (0.57) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385662-B1 | Heterocycles with inhibitory activity of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-13 | — | — | EP | claimed |