SCHEMBL921819

SCHEMBL921819

Cc1cccc(Oc2cccc(C)c2O)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
TRPA1 O75762 2/20 0.54
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
TP53 P04637 2/20 0.44
LMNA P02545 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 2/20 0.42
KMT2A Q03164 4/20 0.40
TSHR P16473 3/20 0.40
MEN1 O00255 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11123942 0.86 ALDH1A1 (0.46) ALDH1A1TRPA1KDM4EHSD17B10LMNA
SCHEMBL11122698 0.86 ALDH1A1 (0.46) ALDH1A1TRPA1HPGDNPC1RAB9A
SCHEMBL6681770 0.85 ALDH1A1 (0.62) ALDH1A1TRPA1GABRA1GABRB2KDM4E
SCHEMBL30358267 0.85 ALDH1A1 (0.50) ALDH1A1TRPA1KDM4EHPGDHSD17B10
SCHEMBL2913336 0.85 ALDH1A1 (0.50) ALDH1A1TRPA1KDM4EHPGDHSD17B10
SCHEMBL10981342 0.83 ALDH1A1 (0.48) ALDH1A1TRPA1GABRA1GABRB2KDM4E
SCHEMBL29661990 0.83 ALDH1A1 (0.67) ALDH1A1TRPA1GABRA1GABRB2KDM4E
SCHEMBL50085 0.83 ALDH1A1 (0.67) ALDH1A1TRPA1GABRA1GABRB2KDM4E
SCHEMBL27854468 0.82 TRPA1 (0.58) ALDH1A1TRPA1KDM4EHPGDHSD17B10
SCHEMBL14434284 0.81 ALDH1A1 (0.56) ALDH1A1TRPA1GABRA1GABRB2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019151504-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF 帝人株式会社 2019-08-08 WO disclosed
CN-105068389-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEM CORP 2015-11-18 CN disclosed
CN-102163013-B Electrophotographic photoreceptor and image forming apparatus using the same MITSUBISHI CHEM CORP 2015-02-18 CN disclosed
CN-102169298-B Image forming apparatus with a plurality of image forming units MITSUBISHI CHEM CORP 2014-01-08 CN disclosed
CN-101334592-B Electrophotographic photoreceptor MITSUBISHI CHEM CORP 2013-11-06 CN disclosed
CN-102156394-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-09-25 CN disclosed
CN-102221793-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-07-31 CN disclosed
CN-102169297-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-07-31 CN disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
CN-102937780-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CO LTD 2013-02-20 CN disclosed
CN-101334592-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2008-12-31 CN disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
CN-1985218-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2007-06-20 CN disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed
EP-0294458-B1 LUBRICANT COMPOSITION The Lubrizol Corporation (US) 1991-08-21 EP disclosed
EP-0245792-B1 PROCESS FOR THE PREPARATION OF CARBOXYLIC-ACID ESTERS BAYER AG (DE) 1991-06-12 EP disclosed
US-5004569-A Using phosphite containing oxetane groups as esterification catalyst BAYER AKTIENGESELLSCHAFT (DE) 1991-04-02 US disclosed
EP-0245792-A2 Process for the preparation of carboxylic-acid esters BAYER AG (DE) 1987-11-19 EP disclosed
US-4225483-A Boric acid esters and oxetanes for stabilizing phosphite-free polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0001823-A2 Use of esters of boric acid to stabilize phosphite-free polycarbonates, and the obtained stabilized polycarbonate moulding compositions BAYER AG (DE) 1979-05-16 EP disclosed