Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220618 | 0.89 | STK17A (0.44) | STK17ASTK17B | |
| SCHEMBL19796124 | 0.87 | MAPT (0.46) | STK17ASTK17B | |
| SCHEMBL19796165 | 0.83 | KCNQ3 (0.44) | — | |
| SCHEMBL12841596 | 0.82 | KCNQ3 (0.41) | STK17ASTK17B | |
| SCHEMBL7664958 | 0.82 | RRM2 (0.47) | — | |
| SCHEMBL7662714 | 0.78 | RRM2 (0.44) | — | |
| SCHEMBL17604124 | 0.78 | KCNQ3 (0.46) | — | |
| SCHEMBL11748511 | 0.76 | MAPT (0.52) | STK17A | |
| SCHEMBL11348193 | 0.75 | STK17A (0.55) | STK17ASTK17B | |
| SCHEMBL4442545 | 0.73 | ADRA2A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252792-A1 | METHODS AND COMPOSITIONS FOR MODULATING RHO-MEDIATED GENE TRANSCRIPTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120252792-A1 | METHODS AND COMPOSITIONS FOR MODULATING RHO-MEDIATED GENE TRANSCRIPTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2011035143-A2 | METHODS AND COMPOSITIONS FOR INHIBITING RHO-MEDIATED DISEASES AND CONDITIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-03-24 | — | — | WO | disclosed |
| CN-1030317-C | Insecticidal composition using nitromethylene compound as active ingredient | SHELL INT RESEARCH (NL) | 1995-11-22 | — | — | CN | disclosed |
| EP-0369526-B1 | Nitromethylene compounds, their preparation and their use as pesticides | SHELL INT RESEARCH (NL) | 1995-07-26 | — | — | EP | disclosed |
| US-5039686-A | Insecticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-08-13 | — | — | US | disclosed |
| CN-1042710-A | Nitromethylene compounds, their preparation method and they are as the purposes of agricultural chemicals | SHELL INT RESEARCH (NL) | 1990-06-06 | — | — | CN | disclosed |
| EP-0369526-A2 | Nitromethylene compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252792-A1 | METHODS AND COMPOSITIONS FOR MODULATING RHO-MEDIATED GENE TRANSCRIPTION | RHOA, RHOC, ROCK1 | STK17A 2930/4885STK17B 2975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.