Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945525 | 0.71 | BCL2L1 (0.48) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL19028377 | 0.71 | BCL2L1 (0.48) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL3961093 | 0.71 | BCL2L1 (0.48) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL37705 | 0.70 | PNMT (0.39) | ALOX15HSD17B10PNMT | |
| Bromide SCHEMBL384160 | 0.69 | BCL2L1 (0.47) | BCL2L1BADDRD2DRD3DRD1 | |
| Hydrochloric Acid SCHEMBL11569899 | 0.69 | BCL2L1 (0.47) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL9218467 | 0.67 | BCL2L1 (0.44) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL3157785 | 0.67 | PNMT (0.67) | BCL2L1BADPNMT | |
| SCHEMBL29914246 | 0.67 | PNMT (0.67) | BCL2L1BADPNMT | |
| Hydrochloric Acid SCHEMBL15056499 | 0.65 | PNMT (0.65) | BCL2L1BADPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | claimed |
| EP-0317292-B1 | NEW ANTIBIOTICS OF THE MUREIDOMYCIN GROUP, THEIR PREPARATION, AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-07 | — | — | EP | claimed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | claimed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | claimed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | claimed |
| JP-1230568-A | — | — | None | — | — | JP | disclosed |
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0317292-B1 | NEW ANTIBIOTICS OF THE MUREIDOMYCIN GROUP, THEIR PREPARATION, AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| JP-H01230568-A | MUREIDOMYCIN DERIVATIVE | SANKYO CO LTD | 1989-09-14 | — | — | JP | disclosed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | disclosed |