Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPOR | P19235 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218471 | 1.00 | GCGR (0.51) | GCGRALDH1A1L3MBTL1POLBEPOR | |
| SCHEMBL2165184 | 0.85 | RECQL (0.55) | ALDH1A1L3MBTL1RECQLMEN1MAPT | |
| SCHEMBL746313 | 0.85 | RECQL (0.55) | ALDH1A1L3MBTL1RECQLMEN1MAPT | |
| SCHEMBL746312 | 0.85 | RECQL (0.55) | ALDH1A1L3MBTL1RECQLMEN1MAPT | |
| SCHEMBL7237043 | 0.85 | GCGR (0.48) | GCGRALDH1A1L3MBTL1POLBEPOR | |
| Methylamine SCHEMBL9389458 | 0.81 | RECQL (0.55) | RECQLMEN1MAPTKMT2ANPC1 | |
| SCHEMBL10888892 | 0.80 | MAPT (0.55) | ALDH1A1L3MBTL1POLBEPORMEN1 | |
| SCHEMBL9325994 | 0.80 | MAPT (0.55) | ALDH1A1L3MBTL1POLBEPORMEN1 | |
| SCHEMBL9325989 | 0.80 | MAPT (0.55) | ALDH1A1L3MBTL1POLBEPORMEN1 | |
| SCHEMBL9798371 | 0.80 | LTA4H (0.54) | ALDH1A1L3MBTL1POLBMAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636124-A1 | 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021170-A1 | 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1993-10-28 | — | — | WO | disclosed |