Methylamine

Methylamine

SCHEMBL9389458

CN.ON=Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.55
NFE2L2 Q16236 1/20 0.50
GAA P10253 1/20 0.48
CASP6 P55212 1/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 2/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
HTR3E A5X5Y0 1/20 0.45
HTR3B O95264 1/20 0.45
HTR3A P46098 1/20 0.45
HTR3D Q70Z44 1/20 0.45
HTR3C Q8WXA8 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2B Q13224 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL746313 0.95 RECQL (0.55) RECQLNFE2L2GAACASP6MEN1
SCHEMBL746312 0.95 RECQL (0.55) RECQLNFE2L2GAACASP6MEN1
SCHEMBL2165184 0.95 RECQL (0.55) RECQLNFE2L2GAACASP6MEN1
SCHEMBL9218471 0.81 GCGR (0.51) RECQLMEN1KMT2ANPC1RAB9A
SCHEMBL9218480 0.81 GCGR (0.51) RECQLMEN1KMT2ANPC1RAB9A
SCHEMBL8274381 0.80 MAPT (0.51) RECQLMEN1KMT2ANPC1RAB9A
SCHEMBL14904519 0.80 NFE2L2 (0.54) RECQLNFE2L2GAACASP6MEN1
SCHEMBL5954099 0.80 RECQL (0.55) RECQLNFE2L2GAACASP6MEN1
SCHEMBL14088919 0.80 MAPT (0.51) RECQLMEN1KMT2ANPC1RAB9A
SCHEMBL5215991 0.80 RECQL (0.55) RECQLNFE2L2GAACASP6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586393-A1 SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES ZENECA LIMITED (GB) 1994-03-16 EP disclosed
WO-1992018487-A1 SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES ZENECA LIMITED (GB) 1992-10-29 WO disclosed