Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833539 | 1.00 | SIGMAR1 (0.33) | SIGMAR1CYP19A1POLBCHRM1 | |
| SCHEMBL9369573 | 0.90 | SIGMAR1 (0.33) | SIGMAR1CYP19A1POLBCHRM1 | |
| SCHEMBL5490043 | 0.90 | SIGMAR1 (0.33) | SIGMAR1CYP19A1POLBCHRM1 | |
| Ammonia Solution, Strong SCHEMBL9603320 | 0.86 | — | — | |
| SCHEMBL8098459 | 0.83 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL9220972 | 0.82 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8832944 | 0.82 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8547165 | 0.78 | ATM (0.50) | SIGMAR1CYP19A1POLBCHRM1 | |
| SCHEMBL7233850 | 0.78 | ATM (0.50) | SIGMAR1CYP19A1POLBCHRM1 | |
| SCHEMBL7597723 | 0.78 | ATM (0.50) | SIGMAR1CYP19A1POLBCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |