SCHEMBL7597723

SCHEMBL7597723

C=CCOC(=O)N1CC(O)C[C@H]1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
POLB P06746 2/20 0.36
MME P08473 1/20 0.35
CYP19A1 P11511 1/20 0.34
SIGMAR1 Q99720 1/20 0.33
CHRM1 P11229 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
RAB9A P51151 1/20 0.33
ACE P12821 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9328664 1.00 ATM (0.50) ATMPOLBMMECYP19A1SIGMAR1
SCHEMBL8547165 1.00 ATM (0.50) ATMPOLBMMECYP19A1SIGMAR1
SCHEMBL7233850 1.00 ATM (0.50) ATMPOLBMMECYP19A1SIGMAR1
SCHEMBL5494161 1.00 ATM (0.50) ATMPOLBMMECYP19A1SIGMAR1
SCHEMBL28339063 0.87 RAB9A (0.38) ATMCYP19A1SIGMAR1CHRM1RAB9A
SCHEMBL8582244 0.84 ALDH1A1 (0.48) ATMPOLBCYP19A1SIGMAR1MEN1
SCHEMBL4637454 0.84 ALDH1A1 (0.48) ATMPOLBCYP19A1SIGMAR1MEN1
SCHEMBL8582242 0.84 ALDH1A1 (0.48) ATMPOLBCYP19A1SIGMAR1MEN1
SCHEMBL6772112 0.83 POLB (0.36) ATMPOLBCYP19A1SIGMAR1
SCHEMBL9386896 0.81 ATM (0.36) ATMCYP19A1SIGMAR1CHRM1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998020350-A1 COMBINATORIAL HYDROXY-AMINO ACID AMIDE LIBRARIES PHARMACOPEIA, INC. (US) 1998-05-14 WO claimed
CN-115053184-B Composition for forming EUV resist underlayer film 日产化学株式会社 2024-12-06 CN disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed
JP-2002097180-A METHOD FOR PRODUCING (2S,4R)-N,N-DIMETHYL-1- ALLYLOXYCARBONYL-4-SUBSTITUTED-2-PYRROLIDINECARBOXAMIDE SUMITOMO CHEM CO LTD 2002-04-02 JP disclosed
EP-0551993-B1 Pyrrolidine derivatives and process for preparing the same SUMITOMO PHARMA (JP) 1996-07-10 EP disclosed
US-5322952-A Pyrrolidine derivatives and process for preparing the same SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1994-06-21 US disclosed
EP-0551993-A1 Pyrrolidine derivatives and process for preparing the same SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1993-07-21 EP disclosed