Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220554 | 0.81 | MALT1 (0.45) | HSD17B3MALT1SMN1; SMN2 | |
| SCHEMBL9213535 | 0.78 | RYR2 (0.49) | SMN1; SMN2 | |
| SCHEMBL9218695 | 0.78 | PTPN1 (0.40) | SRD5A1SRD5A2EDNRBEDNRAPTPN2 | |
| SCHEMBL6404425 | 0.77 | RYR2 (0.41) | TDP1SMN1; SMN2 | |
| SCHEMBL31537554 | 0.76 | PNMT (0.44) | SRD5A1SRD5A2EDNRBEDNRAPNMT | |
| SCHEMBL1016657 | 0.76 | PNMT (0.44) | SRD5A1SRD5A2EDNRBEDNRAPNMT | |
| SCHEMBL3089985 | 0.76 | PNMT (0.44) | SRD5A1SRD5A2EDNRBEDNRAPNMT | |
| SCHEMBL26814042 | 0.76 | PNMT (0.44) | SRD5A1SRD5A2EDNRBEDNRAPNMT | |
| SCHEMBL12060932 | 0.74 | NPC1 (0.39) | SRD5A1SRD5A2EDNRBEDNRAPTPN2 | |
| SCHEMBL9217505 | 0.70 | PNMT (0.33) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389425-B1 | Benzotiopyranyl amines | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| US-5071858-A | Antipsychotic benzothiopyranylamines | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0389425-A1 | Benzotiopyranyl amines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |