Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218692 | 0.81 | SRD5A1 (0.36) | MALT1SMN1; SMN2HSD17B3 | |
| SCHEMBL9213535 | 0.78 | RYR2 (0.49) | SMN1; SMN2 | |
| SCHEMBL9210918 | 0.78 | MALT1 (0.43) | MALT1NOTUMHTR2BHTR2CHTT | |
| SCHEMBL9220559 | 0.78 | MALT1 (0.43) | MALT1NOTUMHTR2BHTR2CKDM4E | |
| SCHEMBL6404425 | 0.77 | RYR2 (0.41) | NOTUMSMN1; SMN2 | |
| SCHEMBL4015666 | 0.76 | PSEN1 (0.42) | NOTUMHTTTSHR | |
| SCHEMBL9209494 | 0.73 | MALT1 (0.38) | MALT1NOTUMHTR2BHTR2CHTR2A | |
| SCHEMBL24440190 | 0.71 | HDAC8 (0.42) | NOTUMHTT | |
| SCHEMBL31262473 | 0.71 | HDAC8 (0.42) | NOTUMHTT | |
| SCHEMBL17443352 | 0.71 | HTR1D (0.46) | NOTUMHTR2CHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389425-B1 | Benzotiopyranyl amines | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| US-5071858-A | Antipsychotic benzothiopyranylamines | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0389425-A1 | Benzotiopyranyl amines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |