Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228166 | 0.88 | ADRB2 (0.55) | L3MBTL1ADRB2KDM4EPKMALDH1A1 | |
| SCHEMBL9219158 | 0.85 | CYP11B1 (0.52) | SYK | |
| SCHEMBL28481944 | 0.82 | AR (0.46) | HPGDADRB2KDM4EPKMALDH1A1 | |
| SCHEMBL31019371 | 0.82 | AR (0.46) | HPGDADRB2KDM4EPKMALDH1A1 | |
| SCHEMBL28158844 | 0.80 | SYK (0.59) | SYKAURKBINCENPMAPTL3MBTL1 | |
| SCHEMBL27540487 | 0.75 | SYK (0.48) | SYKAURKBINCENPMAPTL3MBTL1 | |
| SCHEMBL6932590 | 0.75 | L3MBTL1 (0.45) | MAPTL3MBTL1ADRB2TDP1ALDH1A1 | |
| SCHEMBL5414689 | 0.74 | KDM4E (0.43) | L3MBTL1ADRB2KDM4EPKMALDH1A1 | |
| SCHEMBL5411263 | 0.72 | PTPN11 (0.41) | KDM4EALDH1A1HDAC8 | |
| SCHEMBL28725198 | 0.72 | APP (0.46) | MAPTL3MBTL1HPGDATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412079-A | Liquid crystal monomer compound and polymer obtained therefrom | NIPPON PAINT CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0617110-A1 | Liquid crystal monomer compound and polymer obtained therefrom | Nippon Paint Co., Ltd. (JP) | 1994-09-28 | — | — | EP | disclosed |