Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865190 | 0.73 | KEAP1 (0.47) | RAB9ALMNAMAPTNPC1KDM4E | |
| SCHEMBL10958770 | 0.73 | KMT2A (0.53) | RAB9AMAPTNPC1KDM4EPKM | |
| SCHEMBL7390350 | 0.71 | — | — | |
| SCHEMBL3241469 | 0.70 | MAPT (0.54) | PAMRAB9ALMNAMAPTNPC1 | |
| Biphenyl SCHEMBL27648104 | 0.69 | KMO (0.44) | LMNAKDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5847297 | 0.69 | CYP3A4 (0.34) | LMNACYP2D6MAOB | |
| SCHEMBL5752399 | 0.69 | — | — | |
| SCHEMBL4483981 | 0.69 | — | — | |
| SCHEMBL7361344 | 0.69 | — | — | |
| SCHEMBL10352034 | 0.68 | FEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470834-A | Metalloproteinase enzyme inhibitors for arthritis, rheumatism and cancers | FLORIDA STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |