Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | RGS12 | O14924 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219287 | 0.93 | HMGCR (0.43) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| SCHEMBL9219275 | 0.93 | HMGCR (0.43) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| Butane SCHEMBL9219876 | 0.82 | HMGCR (0.44) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| SCHEMBL9394071 | 0.81 | EGFR (0.45) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| SCHEMBL6911195 | 0.79 | HMGCR (0.47) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| SCHEMBL6917057 | 0.79 | HMGCR (0.47) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| Butane SCHEMBL9220686 | 0.77 | GPR55 (0.42) | HMGCRNR1I2EGFRGPR55SMN1; SMN2 | |
| SCHEMBL6916348 | 0.76 | HMGCR (0.46) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| SCHEMBL5847331 | 0.75 | GABBR2 (0.48) | HMGCRNR1I2EGFRGPR55NPSR1 | |
| SCHEMBL9390290 | 0.75 | GPR55 (0.44) | HMGCRNR1I2EGFRGPR55NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |