Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177605 | 0.91 | ALDH1A1 (0.53) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL1627692 | 0.90 | ALDH1A1 (0.51) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL7693841 | 0.89 | LTA4H (0.50) | LTA4HALDH1A1MAPK1L3MBTL1CCR6 | |
| SCHEMBL27417109 | 0.87 | LTA4H (0.51) | LTA4HALDH1A1MAPK1L3MBTL1CCR6 | |
| SCHEMBL13323438 | 0.87 | ALDH1A1 (0.61) | LTA4HALDH1A1MAPK1L3MBTL1HTT | |
| SCHEMBL24996860 | 0.85 | ALDH1A1 (0.56) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL9820016 | 0.85 | ALDH1A1 (0.56) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL3364814 | 0.85 | ALDH1A1 (0.56) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL5142251 | 0.85 | ALDH1A1 (0.56) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL1005760 | 0.85 | ALDH1A1 (0.56) | LTA4HALDH1A1MAPK1L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |