Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364290 | 0.88 | MAOB (0.52) | TAAR1CA2ALDH1A1 | |
| SCHEMBL13733896 | 0.86 | FNTA (0.54) | ESR1ESR2IDO1TAAR1FNTA | |
| SCHEMBL10793330 | 0.81 | GPR52 (0.49) | TAAR1CYP2C19L3MBTL1 | |
| SCHEMBL9702631 | 0.80 | GPR52 (0.47) | ALDH1A1 | |
| SCHEMBL717373 | 0.79 | ESR1 (0.78) | ESR1ESR2IDO1TAAR1FNTA | |
| SCHEMBL1355705 | 0.78 | TAAR1 (0.56) | ESR1ESR2TAAR1FNTAFNTB | |
| SCHEMBL28432277 | 0.78 | MAOB (0.48) | TAAR1OPRK1ALDH1A1 | |
| SCHEMBL10582013 | 0.78 | TSHR (0.47) | CA2KDM4EALDH1A1 | |
| SCHEMBL156250 | 0.77 | MAOB (0.71) | ESR1ESR2IDO1TAAR1FNTA | |
| SCHEMBL156251 | 0.77 | MAOB (0.71) | ESR1ESR2IDO1TAAR1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470834-A | Metalloproteinase enzyme inhibitors for arthritis, rheumatism and cancers | FLORIDA STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |