Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355796 | 0.90 | ESR1 (0.56) | TAAR1ESR1ESR2CA12CA4 | |
| SCHEMBL1115608 | 0.85 | MAOB (0.46) | TAAR1MAOBALDH1A1 | |
| SCHEMBL2528043 | 0.83 | TAAR1 (0.50) | TAAR1AKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL8709601 | 0.82 | GPR52 (0.49) | TAAR1MAOBCA12CA9ALDH1A1 | |
| SCHEMBL154597 | 0.81 | TAAR1 (0.53) | TAAR1AKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL154598 | 0.81 | TAAR1 (0.53) | TAAR1AKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL4091179 | 0.80 | GPR52 (0.50) | MAPT | |
| SCHEMBL7814468 | 0.80 | NFE2L2 (0.48) | TAAR1MEN1ALDH1A1GAAMAPT | |
| SCHEMBL9219296 | 0.78 | ESR1 (0.48) | TAAR1ESR1ESR2ALDH1A1FNTA | |
| SCHEMBL5632468 | 0.76 | GPR52 (0.54) | TAAR1G6PC1MEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431525-B2 | Coelenteramide analogs | JNC CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20110288280-A1 | COELENTERAMIDE ANALOGS | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-0349062-A1 | Quinoline ether alkanoic acid | MERCK FROSST CANADA INC. (CA) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288280-A1 | COELENTERAMIDE ANALOGS | CCKAR, ARSA, SI | TAAR1 1378/4885AKR1B10 2279/4885AKR1B1 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.