Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | CD69 | Q07108 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638769 | 0.80 | PTGER1 (0.46) | L3MBTL1 | |
| SCHEMBL12961813 | 0.79 | CA1 (0.41) | PTGDR2KMT2ATDP1L3MBTL1PTPN1 | |
| SCHEMBL9428743 | 0.79 | ADRB2 (0.40) | PTGDR2KMT2ATDP1L3MBTL1PTPRC | |
| SCHEMBL4746689 | 0.78 | PTGDR2 (0.57) | PTGDR2KMT2ACD69L3MBTL1ALOX15 | |
| SCHEMBL2561402 | 0.78 | PTGDR2 (0.57) | PTGDR2KMT2ACD69TDP1L3MBTL1 | |
| SCHEMBL23111641 | 0.78 | PTGDR2 (0.57) | PTGDR2KMT2ACD69TDP1ALOX15 | |
| SCHEMBL18095828 | 0.78 | KMT2A (0.72) | PTGDR2KMT2ACD69TDP1ALOX15 | |
| SCHEMBL12646895 | 0.78 | KDM4E (0.44) | TDP1L3MBTL1PTPN1KDM4EGAA | |
| SCHEMBL14042113 | 0.77 | PTGDR2 (0.55) | PTGDR2KMT2ACD69L3MBTL1ALOX15 | |
| SCHEMBL10965074 | 0.77 | MAPT (0.37) | PTGDR2KMT2ATDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |