Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638769 | 0.78 | PTGER1 (0.46) | MAPTHTTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12961813 | 0.77 | CA1 (0.41) | MAPTHTTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10913527 | 0.77 | ALDH1A1 (0.46) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9428743 | 0.77 | ADRB2 (0.40) | HTTL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9219398 | 0.77 | PTGDR2 (0.58) | L3MBTL1PTGDR2KMT2ATDP1GAA | |
| SCHEMBL12646895 | 0.75 | KDM4E (0.44) | HTTL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7362517 | 0.75 | ALDH1A1 (0.61) | MAPTHTTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1642697 | 0.73 | CA1 (0.56) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL3273244 | 0.73 | CA1 (0.40) | MAPTHTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11229642 | 0.72 | CD274 (0.37) | HTTALDH1A1SMN1; SMN2HPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492703-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |