Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323455 | 0.84 | KDM4E (0.40) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL841261 | 0.75 | MEN1 (0.56) | KDM4ERECQLMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6737822 | 0.73 | MEN1 (0.55) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL8322237 | 0.70 | KDM4E (0.43) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL20551143 | 0.68 | KDM4E (0.38) | KDM4ERECQLLMNATSHRNPSR1 | |
| SCHEMBL18740061 | 0.67 | LMNA (0.35) | KDM4ERECQLLMNATSHRNPSR1 | |
| SCHEMBL10920419 | 0.66 | PLAT (0.32) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL22286156 | 0.65 | KDM4E (0.35) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL9218403 | 0.65 | LMNA (0.34) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL20550738 | 0.65 | SRC (0.42) | KDM4EMEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |