Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323455 | 0.86 | KDM4E (0.40) | KDM4ERECQLLMNAGAAMEN1 | |
| SCHEMBL5282340 | 0.79 | MEN1 (0.55) | KDM4ERECQLLMNAMEN1KMT2A | |
| SCHEMBL8327318 | 0.75 | KDM4E (0.38) | KDM4ERECQLLMNAPOLB | |
| SCHEMBL20551143 | 0.73 | KDM4E (0.38) | KDM4ERECQLLMNAGAAALDH1A1 | |
| SCHEMBL939241 | 0.71 | KDM4E (0.35) | KDM4ERECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9219783 | 0.70 | KDM4E (0.38) | KDM4ERECQLLMNAGAAMEN1 | |
| SCHEMBL31081858 | 0.69 | ALDH1A1 (0.36) | KDM4ERECQLLMNAMEN1KMT2A | |
| SCHEMBL22286228 | 0.69 | MAPK1 (0.46) | KDM4ERECQLLMNAGAAMEN1 | |
| SCHEMBL16200178 | 0.68 | KDM4E (0.44) | KDM4ERECQLNLRP3CCR1TDP1 | |
| SCHEMBL29658144 | 0.68 | MEN1 (0.35) | KDM4ERECQLLMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789698-B1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5763359-A | N-(1-ethyl-4-pyrazolyl)triazoloazinesulfonamide herbicides | DOW AGROSCIENCES LLC (US) | 1998-06-09 | — | — | US | disclosed |