Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209794 | 0.87 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9211094 | 0.85 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9221643 | 0.84 | MTNR1A (0.36) | MAPTS1PR1S1PR3MTNR1AMTNR1B | |
| SCHEMBL9215417 | 0.82 | MEN1 (0.36) | NPC1RAB9AL3MBTL1PKMMEN1 | |
| SCHEMBL9209788 | 0.81 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9211087 | 0.79 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9219849 | 0.77 | MTNR1A (0.35) | MAPTMTNR1AMTNR1B | |
| SCHEMBL9215312 | 0.77 | MAPT (0.34) | NPC1RAB9AL3MBTL1MAPTMEN1 | |
| SCHEMBL9275150 | 0.76 | MEN1 (0.37) | L3MBTL1MEN1KMT2AFFAR1MTNR1A | |
| SCHEMBL9313258 | 0.76 | FFAR1 (0.48) | SMN1; SMN2MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |