Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275150 | 0.93 | MEN1 (0.37) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9215312 | 0.92 | MAPT (0.34) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9212152 | 0.89 | PPARG (0.34) | MEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL9219849 | 0.88 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL9211525 | 0.86 | NPC1 (0.36) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9212889 | 0.84 | FFAR1 (0.36) | KMT2AFFAR1S1PR1 | |
| SCHEMBL9219323 | 0.83 | PPARG (0.36) | MEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL9220136 | 0.82 | NPC1 (0.35) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9216433 | 0.81 | MTNR1A (0.33) | MTNR1AMTNR1BFFAR1 | |
| SCHEMBL9221643 | 0.80 | MTNR1A (0.36) | MTNR1AMTNR1BS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | claimed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | claimed |
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | disclosed |