Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878819 | 0.84 | TSHR (0.36) | POLBAPEX1HPGDPPOXSMN1; SMN2 | |
| SCHEMBL8876677 | 0.83 | EPHX2 (0.36) | POLBHPGDPPOXNPC1RAB9A | |
| SCHEMBL8879992 | 0.83 | HPGD (0.33) | POLBAPEX1HPGDPPOXNPC1 | |
| SCHEMBL9211922 | 0.80 | PPOX (0.36) | POLBHPGDPPOXSMN1; SMN2MAPT | |
| SCHEMBL8878084 | 0.78 | SMN1; SMN2 (0.39) | POLBHPGDPPOXSMN1; SMN2MAPT | |
| SCHEMBL8879045 | 0.76 | PPOX (0.35) | PPOXALDH1A1 | |
| SCHEMBL8883340 | 0.74 | PPOX (0.33) | PPOX | |
| SCHEMBL9843857 | 0.74 | PPOX (0.41) | HPGDPPOXSMN1; SMN2ALDH1A1 | |
| SCHEMBL8878270 | 0.72 | DPP4 (0.38) | PPOX | |
| SCHEMBL8878887 | 0.72 | PPOX (0.34) | PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415642-B1 | Glutarimides | ROHM & HAAS (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |