Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211922 | 0.86 | PPOX (0.36) | SMN1; SMN2MAPTLMNAHPGDPPOX | |
| SCHEMBL8878819 | 0.81 | TSHR (0.36) | SMN1; SMN2LMNAHPGDPPOXALDH1A1 | |
| SCHEMBL8876677 | 0.80 | EPHX2 (0.36) | SMN1; SMN2MAPTLMNAHPGDPPOX | |
| SCHEMBL8879992 | 0.80 | HPGD (0.33) | SMN1; SMN2MAPTHPGDPPOXTSHR | |
| SCHEMBL9220170 | 0.78 | POLB (0.37) | SMN1; SMN2MAPTLMNAHPGDPPOX | |
| SCHEMBL8877805 | 0.76 | PPOX (0.38) | PPOX | |
| SCHEMBL8877808 | 0.75 | PPOX (0.40) | PPOX | |
| SCHEMBL9250353 | 0.74 | HPGD (0.63) | SMN1; SMN2MAPTLMNAHPGDGAA | |
| SCHEMBL8879045 | 0.74 | PPOX (0.35) | PPOXALDH1A1 | |
| SCHEMBL8878503 | 0.74 | PPOX (0.32) | PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5502027-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0415642-B1 | Glutarimides | ROHM & HAAS (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |