SCHEMBL9220402

SCHEMBL9220402

CCC(C)(O)c1ccc(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CASR P41180 4/20 0.41
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
AR P10275 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
CYP2C9 P11712 1/20 0.33
PDE2A O00408 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
VDR P11473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12525117 0.82 TP53 (0.41) CASRTP53TDP1MEN1KMT2A
SCHEMBL12180439 0.79 TDP1 (0.46) CASRTP53TDP1MEN1KMT2A
SCHEMBL18546040 0.79 CASR (0.53) CASRTP53TDP1MEN1KMT2A
SCHEMBL7610097 0.79 TDP1 (0.46) CASRTP53TDP1MEN1KMT2A
SCHEMBL18794054 0.78 CASR (0.38) CASRTP53TDP1MEN1KMT2A
SCHEMBL18802823 0.77 ESR1 (0.35) TP53ARESR1ESR2CYP2C9
SCHEMBL13703290 0.76 MAPT (0.40) CASRTP53TDP1MEN1KMT2A
SCHEMBL19130505 0.75 GABRA1 (0.42) CASRTDP1MEN1KMT2AMAPT
SCHEMBL7127844 0.75 GABRA1 (0.42) CASRTDP1MEN1KMT2AMAPT
SCHEMBL28046060 0.74 ESR1 (0.36) CASRTP53TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995000114-A1 TETRALINE® FORMATE ESTER AROMA CHEMICALS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
US-5292719-A Perfumes, colognes, soaps and cosmetics; musk aroma UNION CAMP CORPORATION (US) 1994-03-08 US disclosed