Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130505 | 1.00 | GABRA1 (0.42) | GABRA1GABRB2CASRTSHRACHE | |
| SCHEMBL7574531 | 0.86 | TSHR (0.42) | GABRA1GABRB2TSHRHSP90AA1HSP90AB1 | |
| SCHEMBL3641431 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2CASRTSHRACHE | |
| SCHEMBL11102781 | 0.80 | CD44 (0.42) | GABRA1GABRB2CASRHSP90AA1HSP90AB1 | |
| SCHEMBL10599295 | 0.80 | ALDH1A1 (0.38) | GABRA1GABRB2TSHRHSP90AA1HSP90AB1 | |
| SCHEMBL13462898 | 0.80 | TSHR (0.39) | GABRA1GABRB2CASRTSHRACHE | |
| SCHEMBL7550163 | 0.78 | ALDH1A1 (0.58) | GABRA1GABRB2TSHRHSP90AA1HSP90AB1 | |
| SCHEMBL18766199 | 0.78 | MEN1 (0.47) | GABRA1GABRB2CASRHSP90AA1ALDH1A1 | |
| SCHEMBL4352221 | 0.77 | TSHR (0.41) | GABRA1GABRB2CASRTSHRACHE | |
| SCHEMBL24538831 | 0.77 | RIPK1 (0.40) | TSHRHSP90AA1HSP90AB1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660884-B2 | Catalyst promote synthesis of tertiary alcohols with enantioselectivity; Bicyclo(2.2.1)heptane-1-methane sulfonamide-N,N'-(1S,2S)-1,2-cyclohexanediylbis(2-hydroxy-7,7-dimethyl) -(1R,1'R,2S,2'S,4S,4'S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2003-12-09 | — | — | US | disclosed |
| US-20030191345-A1 | CATALYSTS, METHODS FOR MAKING SAID CATALYSTS, AND METHODS FOR MAKING CHIRAL COMPOUNDS WITH HIGH ENANTIOSELECTIVITY | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191345-A1 | CATALYSTS, METHODS FOR MAKING SAID CATALYSTS, AND METHODS FOR MAKING CHIRAL COMPOUNDS WITH HIGH ENANTIOSELECTIVITY | COASY, HMGCR, ALKBH1 | GABRA1 3670/4885GABRB2 3649/4885CASR 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.